Geo-Resilience Framework
The strategic framework for global resilience architectures

Strategic Moves in 360° Mode – Navigating with the Geo-Resilience Compass

Successfully addressing complex health risks such as Long COVID, ME/CFS, MCS, and zoonotic threats requires far more than medical expertise. It demands a strategic architecture that interlinks global resilience, semantic integrity, and context-sensitive action. This is precisely where the Geo-Resilience Compass comes into play: as a dynamic navigation instrument that not only provides orientation but enables targeted strategic moves — along spatio-temporal challenges and systemic interfaces.

The selection of relevant “players” presented here is not a static model, but a curated playing field. It forms the foundation for strategic movements within a multidimensional space, where environment, health, infrastructure, and society are not understood as separate silos, but as interwoven systems. Each actor represents a deliberate move — whether for detection, regulation, prevention or restoration.

This list is intentionally multipolar, interdisciplinary, and semantically precise. It includes international organizations, space agencies, environmental and health institutions, AI and EO platforms, biobanks, patient networks, indigenous monitoring programs, toxicology experts, micronutrient researchers, database developers, start-ups and visionary individuals. Their roles reflect the eight strategic compass directions — from early warning systems and adaptive infrastructure to societal stabilization and semantic coherence.

The order in which the actors are listed does not imply any ranking. All participants are equally important and contribute essentially to the overall strategic process. The challenges we face — whether natural disasters, biological risks, or digital vulnerability — are too complex, too interconnected, and too dynamic to be solved in isolation.

I have chosen this 360° approach to systematically capture all relevant aspects and pursue the goal of a strategic “checkmate” against these diseases and risks. It will require many targeted moves — but I am convinced: if we maintain the holistic perspective and use the compass as an open system, we can overcome these challenges together.


Diseases and disasters know no boundaries and they unite humanity through shared vulnerability, whether it be long COVID, extreme weather events, earthquakes, environmental toxins or supply chain disruptions. The actors mentioned here are (only) a selection of key players, but the game requires comprehensive, dynamic participation — from local communities to supranational organizations.

Global Governance & Disaster Coordination

Actors with a mandate for control, coordination, early warning, and semantic resilience architecture

  • UN-OCHA / WHO / UNESCO / UNDRR / UNIDIR / UNEP / UNO / OECD
  • World Economic Forum (WEF) / FEMA / FAO / WOAH (OIE) / Red Cross
  • IEEE & GRSS Disaster Management & Early Warning Working Group (Ing. Hassan Abouseda, Dr. Siri Jodha Singh Khalsa & Team)
  • ASEAN Coordinating Centre for Humanitarian Assistance (AHA Centre)
  • CAREC Institute / ICC (Inuit Circumpolar Council) / ISO/TC 211
  • ACAPS / Global Partnership for AI (GPAI) / OECD.AI Observatory
  • CrisisReady / Harvard / Direct Relief
  • World Bank / GFDRR (Global Facility for Disaster Reduction and Recovery)
  • Prepared International – Expert network for DRR & resilience projects
  • PreventionWeb Directory – over 1,000 DRR actors worldwide

Actors with a mandate for control, coordination, early warning, and semantic resilience architecture

  • Erin Martin (EOTEC DevNet)
  • Jehad Abualrob, as Head of the Department of Health Quality and Occupational Health and Safety at Modern University College (Palestine), contributes to disaster resilience through a governance-adjacent mandate focused (Occupational health systems as stabilizing infrastructure in fragile regions / Health quality assurance as a semantic backbone for early warning and continuity / Crisis management research with relevance to wartime and post-conflict recovery)

Community-Based Disaster Management & Social Capital Systems

  • Professor Jeff Donaldson (Preparedness Labs Inc. (researches social capital formation, community resilience, trust architectures, and communicative disaster preparedness)) & Tristan Claridge
  • Dr. Arthur J. Simental (Developers of Disaster Wargaming modules)

Disaster Policy & Semantic Emergency Management

  • Jessica Jensen is a senior policy researcher at RAND. (Strategic realignment of disaster management as a semantically networked governance system / Research on early warning systems, Incident Command System (ICS), NIMS, and resilience policy)

Crisis Communication & Risk Governance Interfaces

  • Dr. Riem Khalil is a consultant, university lecturer, and social scientist specializing in: Crisis management and risk communication in institutional, social and political contexts


Earth Observation & Spatial Intelligence

Platforms and agencies for EO data, early warning systems and geobased resilience

  • NASA / NASA ARSET / UN-SPIDER / Copernicus/CEMS / Sentinel Hub / OpenEO
  • ISRO (Indien) / CNSA (China) / Roscosmos (Russland) / SUPARCO / LAPAN / SANSA / INPE
  • GEO (Group on Earth Observations) / WMO / CEOS / Planet Labs / ESRI Public Health
  • RCMRD (Nairobi) / SERVIR Amazonia / Digital Earth Africa / Asia / Latin America
  • Humanitarian OpenStreetMap Team (HOT)
  • Can be supplemented with semantic EO integration tools (e.g., OpenEO, ESRI Public Health): Jerry Chong is an internationally networked enterprise architect, working as domain lead architect and domain cloud architect at DHL, as well as Alibaba Cloud MVP.


 Regional Experts & Geo-Resilience Architects

Scientists from geopolitically relevant regions with a focus on resilience and governance

  • Prof. Cui Peng / Prof. Yang Saini / Prof. Hao Zhu & Xing Zhu / Prof. Maya Negev / Prof. Bruria Adini / Prof. Nadav Davidovitch / Prof. Ramesh Ramaswamy / Prof. M. Mohapatra / Prof. Ali Ardalan / Dr. Abbas Ostadtaghizadeh / Dr. Belayneh Fentahun Shibesh / Prof. Dawit Kanito / Dr. Kalim Al-Mahmoud / Dr. Paul S. Roy / Mykhaylo Khvesyk & Mariia Ilina / Dr. Iman Nuwayhid & Rima R. Habib / Abdalftah Hamed Ali / Yaryna Andrushko / Dr. Tanzeel M. A. Omer / Tarig Alhaj Rakhy & Hala Abushama


Biomedical Research & Personalized Medicine

Research institutions, databases, and experts on chronic diseases and PGX

  • NIH / FDA / EMA / CPIC / PharmVar / BioBank Graz / Shanghai Zhangjiang Biobank
  • These technology players do not act as individual players in my strategic “chess game,” but rather as a strategically orchestrated network. Together, they form the semantic infrastructure that operationalizes the Geo-Resilience Compass in its full depth — along all eight axes, from early warning to semantic pattern recognition and auditable decision logic to the restoration of vulnerable systems. Their complementary capabilities in cloud infrastructure, AI, PGX, biobank integration, governance, and digital security enable a multipolar, interoperable resilience architecture that makes human-AI collaboration scalable and institutionally connectable: IBM Watson / Palantir / Oracle (Database and cloud infrastructure for health data, PGX, biobank management) / Microsoft (Azure AI, Microsoft Cloud for Healthcare, Microsoft Research) / Google (KI, Earth Engine, DeepMind Health, Verily Life Sciences) / NVIDIA / Intel / Amazon (Cloud infrastructure for biobanks, PGX, AI-supported diagnostics) / Kaspersky / SAP / Salesforce / ServiceNow (Process control, semantic governance, healthcare logistics), Huawei, BGI Genomics, Tencent, Alibaba Cloud und iCarbonX / Graphcore / Cloudera / Meta/Facebook / Siemens and many other important players
  • Strategic AI Architects (personalized platforms with semantic decision logic): Nissim Titan (4Cast), Dotan Shaniv, Ryan Stoffko (OPP Neuro SPA), Peter Groenen (AI for pharma resilience)
  • Genetic providers / Illumina / Thermo Fisher Scientific / Agilent Technologies / Global Alliance for Genomics and Health (GA4GH) / BC Platforms
  • Medical Medium (Anthony William) / Dr. Shilpa Thakur / Dr. Uwe Gröber
  • Mayo Clinic / Horizon Lab Company
  • Prof. Eric Chan (NUS Singapore) / Prof. Carmen Scheibenbogen / Prof. Uta Behrends / Prof. Kevin Kavanagh / Prof. Magnus Ingelmann-Sundberg / Prof. Hannelore Daniel / Prof. Robert Murphy / Prof. Jianzhong Wang / Prof. Antonella Bertazzo / Prof. Youssef Daali / Prof. Ram Shankar Upadhayaya / Prof. Henk-Jan-Guchelaar / Prof. Erwin Loh / Prof. Yohannes Hagos / Dr. Maureen Miller /  Prof. David F. Putrino / Dr. Ziyad Al-Aly / Dr. William Wallace / Dr. Eric Topol
  • PRECISEU Project – Horizon Europe (25 partners)
  • Memorial Healthcare System / National Healthcare Group / Kmch Research Foundation


Institutional Platforms & Educational Networks

Academic institutions, simulation facilities, and regulatory networks

  • CeMM (Wien) / Helmholtz Munich / University College London / University of Cambridge / University of Montreal / Zhejiang University / NYSIM (CUNY & NYU Langone Health)
  • ERAU (Prof. Alexander Siedschlag)
  • FEAM (Brüssel) / AACT / PAN Germany / MedWatch / EudraVigilance
  • Educational institutions, ministries, legal and security bodies


Environmental Toxicology & Resilience Science

Experts and institutions for environmental health, pollutant management and resilience research

  • Prof. Thomas Backhaus / Dr. Joëlle Rüegg / Dr. Lyle D. Burgoon / Prof. Taosheng Chen / Prof. Beatrice Opeolu / Prof. S. Venkata Mohan / Prof. Monica Lopes-Ferreira / Prof. Carlos Afonso Nogueira / Prof. Shinsuke Tanabe / Prof. Jong-Ju Ahn / Michael F. Hughes (EPA)
  • Boban Cekovic CBRNe & HAZMAT Response Architect – operational early warning, detection, and semantic decontamination systems
  • Bob Small (Black Swan), CBRNE/HAZMAT & Collapse-Resilient Doctrine
  • Hélène Grosbois is an ecological systems thinker focusing on biodiversity and chemical risks.
  • UNEP PEDRR Partnership – Ecosystem-based DRR strategies
  • PAN Germany / Munich Environmental Institute / 
  • ZALF / ISME / Swiss TPH / LSHTM / African Disaster Mitigation Research Center (ADMiR)
  • GISRS / GenBank / NCBI / EMBL-EBI / GISAID
  • MedWatch (FDA / USA) / EudraVigilance – Adverse reaction monitoring


Neuroscience, Nutrition & Systems-Level Innovation

Research on neuroimmunological diseases, micronutrients and systemic transformation

  • Dr. Amine Zorgani – The Microbiome Mavericks / Kent Jones – Accessibility & MS Advocacy / Janice Goh – Coffee Simulator / Christoph & Philipp Ströck – WE&ME Stiftung / Daniel Epstein / Andrew Michaelson / Evonne Fouesnant / Dotan Shaniv / Peter Groenen / Miguel Angel Cabrera-Pérez / Luoheng Qin – InSilico Medicine 
  • Boston Scientific
  • Solution Group (Beijing)


Patient Advocacy, Civil Society & MedTech

Organizations, startups, and movements for patient rights, medtech, and social resilience

  • The many valuable patient organizations and associations
  • Healthcare providers, pharmacists, biobanks, insurers, MedSafetyWeek organizers
  • GNDR – Global Network of Civil Society Organisations for Disaster Reduction
  • Angel and venture communities / Environmental physicians / Biomedical scientists
  • Pharmaceutical and vaccine manufacturers (from AbbVie to ViiV Healthcare GmbH)
  • MedTech Pharma 
  • support association: OrphanHealthcare (Dr. Frank Grossmann)
  • Disaster Management Strategies for Long COVID, ME/CFS, MCS
  • BAYER / vfa – Research-Based Pharmaceutical Companies
  • MedTech Pharma / Software and technology companies, start-ups


Geo-Resilience Compass Matrix – Strategic Allocation by Directional Logic

Center – Resilience Backbone
Mandat:

  • Reflexive decision-making logic
  • Adaptive coordination mechanisms
  • Trust, participation, and semantic openness
  • Integration of anticipation, structuring, and implementation

These example actors form a semantic backbone of the compass. They are not sectoral, but structuring: they enable, connect, coordinate, and reflect. Their role is not operational, but architectural — exactly what the central axis requires.


North – Environmental Change & Legacy Contaminants
Mandat:

  • Shifts in ecosystems and land use
  • Management of pollutants and legacy contamination
  • Soil, water and air resilience
  • Early indicators of environmental stress

These example actors are central to the recording, evaluation, and control of ecological stressors. They combine contaminated site management, environmental monitoring, and early warning with global relevance. Their role is not only scientific, but also strategically operationalizable in terms of compass logic.


Northeast – Early Warning & Risk Detection
Mandat:

  • Integration of Earth observation, sensors, and real-time data
  • Pattern recognition for natural hazards and health risks
  • Scenario development and anticipatory planning
  • Cross-sectoral data logic

Together, these example actors form a semantically coherent early warning cluster: they deliver, network, and operationalize real-time data, pattern recognition and cross-sector risk analytics. Their role is not only technical, but also strategically compatible with governance, scenario development and resilient planning.


East – Health & Biological Risks
Mandat:

  • Zoonoses, pandemics, and microbiological risks
  • Stabilization of supply and care systems
  • Prevention and monitoring
  • Interfaces between environmental and health systems

These example actors form a semantically coherent cluster for biological risks and supply systems. They connect zoonoses, PGX, biobanks, prevention, and environment–health interfaces on a global level. Their role is not only medical, but also strategically networkable for resilient health architectures.


Southeast – Coordinated Care & Adaptive Infrastructure
Mandat:
  • Mobile supply units as an expression of closeness and care
  • Logistics as a connection
  • EO as support for local self-organization
  • Planning as facilitation

These example actors form a semantically coherent cluster for coordinated care and adaptive infrastructure. They combine technological platforms, logistical control, and mobile care units with the aim of operationalizing proximity, self-organization, and planning as enablers. Their role is not only supportive, but also strategically compatible with resilient care systems.


South – Infrastructure & Restoration
Mandat:
  • Protection and reconstruction of critical infrastructure
  • Planning of resilience zones
  • Adaptation to natural hazards (floods, heavy rainfall, earthquakes)
  • Technical robustness and restart strategies
These example actors form a semantically coherent cluster for protection, restoration, and technical resilience. They combine global governance, medical care, infrastructure planning, and restart strategies. Their role is not only reactive, but also strategically compatible for the long-term stabilization of vulnerable systems.


Southwest – Local Continuity & Community Reconnection
Mandat:
  • Education, culture, and local networks
  • Social sensitivity and collective recovery
  • Reconnection of vulnerable groups
  • Promotion of proximity, trust, and community resilience
These example actors form a semantically coherent cluster for social reconnection, local continuity, and collective resilience. They combine education, culture, emotional closeness, and community self-organization with the aim of stabilizing vulnerable groups and strengthening local networks. Their role is not only supportive but transformative for the restoration of social cohesion.


West – Societal Adaptation & Stabilization
Mandat:
  • Local adaptation and functional self-organization
  • Everyday stabilization and social coherence
  • Governance-related structures, educational and legal systems
  • Integration of social, cultural, and regulatory resilience factors
These example actors form a semantically coherent cluster for social adaptation and functional stabilization. They combine governance, education, social cohesion, and cultural self-organization to form a stabilizing backbone for resilient societies. Their role is not only normative, but also operationally compatible with everyday resilience and social restoration.



Northwest – System Coherence & Communication Architectures
Mandat:
  • Interface alignment across sectors and disciplines
  • Structuring information flows under uncertainty
  • Semantic connectivity and interoperability
  • Architectures for strategic communication and decision support
These example actors form a semantically coherent cluster for interface logic, information architecture, and uncertainty navigation. They combine technological platforms, semantic standardization, and strategic communication models to form a stable backbone for systemic resilience. Their role is not only structural, but also decision-supporting and interoperable for complex crisis scenarios.